Co-trimoxazole toxicity.
نویسندگان
چکیده
منابع مشابه
Toxicity of co-trimoxazole in nutritional haematinic deficiency.
Introduction Co-trimoxazole is an antibacterial combination of trimethoprim and sulphamethoxazole which acts by sequentially blockading folate metabolism (Elion, Singer & Hitchings, 1954; Darrell, Garrod & Waterworth, 1968). Cases of haematological toxicity have been reported following its use in patients with initially normal haematological status (Kahn, Fein & Brodsky, 1968; Paulley, 1970; Mc...
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A 15 year old boy presented with two episodes of aseptic meningitis-like reactions after ingestion of co-trimoxazole. The diagnosis of co-trimoxazole induced aseptic meningitis was made. This syndrome should be considered in the differential diagnosis of aseptic meningitis.
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An 80-year-old woman was admitted to hospital with a fractured neck of the femur, which was managed by internal fixation. Antibiotic cover was not provided for the operation. On the sixth day after operation she developed a fever, which was clinically attributed to a urinary infection, although no organism was subsequently cultured. Treatment was started with cotrimoxazole (Septrin), two tablet...
متن کاملThrombophlebitis migrans following co-trimoxazole therapy.
We report an unusual and severe vasculitic disorder following co-trimoxazole, given orally for a urinary tract infection. The vasculitis was manifest solely as thrombophlebitis migrans and involving only veins without evidence of polyarteritis nodosa, or underlying malignancy.
متن کاملCo-trimoxazole red cell aplasia in leukaemia.
A 4 year old boy with acute lymphoblastic leukaemia developed a pure red cell aplasia 13 months after entering remission and while on maintenance chemotherapy. Co-trimoxazole was also being administered for prophylaxis against Pneumocystis carinii infection. When co-trimoxazole was stopped the red cell aplasia resolved.
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ژورنال
عنوان ژورنال: BMJ
سال: 1985
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.291.6493.481